A new textbook on Hematopoiesis has been published by CRC Press/Apple Academic Press, Taylor and Francis, USA (ISBN: 9781003413059) which was edited by Prof. Ravi Kumar Gutti of Department of Biochemistry, School of Life Sciences of University of Hyderabad. The book titled “Hematopoiesis: Biochemical, Cellular, Molecular, and Genomic Perspectives” will be valuable to clinicians, medical school students, and researchers working in the area of hematology.
This book provides valuable information related to developments in hematopoiesis that will be helpful for understanding the basics of hematopoiesis and the clinical treatment of blood diseases. It discusses the widespread concerns of hematopoietic challenges in different and emerging ways. With chapters written by faculty and researchers from prestigious institutions working directly in hematopoiesis and advanced areas of biology, the book offers a comprehensive overview of the regulation of blood cell development, epigenetic mechanisms, and regulatory non-coding RNAs. It presents concepts related to regulation of hematopoietic stem cell development, as well as survival, proliferation, and differentiation. It also discusses the microenvironmental niche where stem cells exist and develop into distinct blood cell types. A model system used to study non-coding RNA functions along with transformation of normal cells into cancer cell is elaborated on as well. Key features of the book:
• Details how to utilize the available investigative tools and techniques to isolate and study single blood cells in different model systems
• Discusses the epigenetics of hematopoiesis
• Considers the clinical outcomes of defective hematopoiesis
• Describes hematopoiesis and cancer stem cells
• Looks at hematopoiesis in relation to specific diseases, such as minimal residual disease (MRD) and leukemia
Prof. Ravi Kumar Gutti is a faculty of Department of Biochemistry and has extensive research and teaching experience from Harvard Medical School (USA), National Institutes of Health (USA), Moffitt Cancer and Research Centre (USA), and RWTH Aachen (Germany). His research expertise primarily focuses on understanding the molecular mechanisms in low platelet diseases and is well funded by granting agencies of the Government of India. He has received awards and recognition from several prominent national and international organizations for making significant contributions to teaching and research. He has authored several publications in reputed international journals and has presented his research work at international scientific meetings.