Key Reaction Developed at the School of Chemistry is Highlighted in the Synthesis of Potent Anticancer Molecules

Ramachary-Bressy-Wang [3+2]-Cycloaddition Reaction: Synthesis of Fully Decorated 1,2,3-Triazoles as Potent Anticancer and EGFR Inhibitors is an article recently published in the Journal of Molecular Structure [https://doi.org/10.1016/j.molstruc.2022.132975]. What’s more interesting is that this work uses one of the organocatalytic click reactions developed at the School of Chemistry represented by Professor D B  Ramachary laboratory at the University of Hyderabad.

Prof. D B Ramachary

Professor Ramachary shares, “Every year cancer touches around 20 million people all over the world instigating expiries estimated in millions. Undesirably, a number of new cancer cases are still growing and approximately 30 million people will be recognized with carcinoma by 2040 in well-developed nations. Therefore, the use of new cancer treatments or active drugs has always been the utmost requirement and task for the current medicine”. I am happy that our reaction is being used by fellow researchers in identifying treatments for this. We have simplified the organocatalytic click reaction in such a way that the process is economical and sustainable, he added.

The above research paper is published by Dr. S. Narsimha, Associate Professor, Department of Chemistry, Chaitanya (Deemed to be University), Warangal and team members.

It can be accessed at: https://www.sciencedirect.com/science/article/pii/S0022286022006445?via%3Dihub